Human clinical data for KPV specifically is limited, but the anti-inflammatory pathway it targets (NF-kB) is one of the most studied mechanisms in medicine
One of those patients is 53-year-old Jenn Rossum, who said she turned to the program with her doctor's approval because she was frustrated that she couldn't lose 20 extra pounds despite skiing, biking and working out most days of the week
Notably, GIP exerts several metabolic actions on extra-pancreatic tissues including adipose tissue, brain and bone (Fig
Neuroscience 335:207220 Mosley RL, Benner EJ, Kadiu I, Thomas M, Boska MD, Hasan K, Laurie C, Gendelman HE (2006) Neuroinflammation, oxidative stress and the pathogenesis of Parkinsons disease