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Drug stability: principles and practices

[1] [24] Although there is some evidence from meta-analyses that L-carnitine supplementation improved cardiac function in people with heart failure, there is insufficient research to determine its overall efficacy in lowering the risk or treating cardiovascular diseases

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In research observations, this is associated with: Strong appetite suppression Significant reduction in reward-driven feeding behavior In some research subjects , a greater tendency toward reduced reward responsiveness or emotional flattening This likely reflects relatively strong central effects on satiety and reward-related pathways in susceptible lab subjects