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SalB inhibits the CD36-mediated PI3K/AKT pathway, downregulates the expression of fibrosis-associated molecules such as CoI, Co, FN, and -SMA, and blocks the pathologic fibrotic process in vitro and in vivo (Yan et al., 2023)
Regulatory uncertainty limits its medical positioning, currently placing it in the grey zone of experimental peptides These limitations make clinical endorsement premature, especially in regulated health systems or for medical-grade use
Diotallevi M, Checconi P, Palamara AT, et al
A well-designed peptide stack addresses these interconnected systems together rather than one at a time
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