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Clinicians should counsel patients that GI side effects during dose escalation may transiently reduce sexual interest before the longer-term hormonal benefits of weight loss accumulate
3 The result is a quiet population of adults who skip medical appointments, postpone vaccinations, decline blood tests, and put off treatments they actually need
Inconsistent dosing can lead to the return of hunger cues and food noise, which may result in higher caloric intake and a slower rate of loss
Finally, the results of one randomized controlled trial in 601 patients with common forms of retinitis pigmentosa indicated that supplementation with 400 IU/day of synthetic vitamin E (equivalent to 180 mg/day of RRR --tocopherol) modestly but significantly accelerated the loss of retinal function compared to placebo (123)
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