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Exenatide contains a glycine at position 2, rendering it less susceptible to DPP-IV degradation, and includes a C-terminal extension (CEX), which stabilises the secondary structure of the hormone, increasing its solubility in physiological buffer
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(2025) 197:E797809
AC-NLE-Cyclo[ASP-His-D-Phe-Arg-TRP-Lys]-NH2
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