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Slower titration for sensitive patients If you experienced significant GI side effects on semaglutide, your provider may recommend a slower approach: Staying at 2.5 mg for 6 to 8 weeks instead of 4 Moving to 3.75 mg (compounded only) before 5 mg Extending each dose level by 2 weeks based on side effect severity This conservative approach takes longer to reach therapeutic doses but results in better long-term adherence

Contact your Get Thin MD Care Coach or pharmacy to confirm whether the medication is still safe to use

Retatrutide should not be used by anyone who is pregnant, breastfeeding, or has an existing health condition