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For the body to resist these damages, it possesses a range of endogenous antioxidants, primarily enzymatic antioxidants (superoxide dismutase (SOD), glutathione peroxidase (GPX), glutathione S-transferase (GST), glutathione reductase (GR), thioredoxin reductase (TrxR), catalase (CAT), etc.), and nonenzymatic antioxidants (glutathione (GSH), bilirubin, ubiquinone, etc.) [11]
H.LiangS
Clinical studies looking at the association between major depressive disorder and sleep disturbances provide further evidence of this relationship
In practice, simultaneous application is problematic: a 2022 Journal of Cosmetic Dermatology study found that applying both at the same time increased transepidermal water loss by 41% and produced 3.2 times more self-reported stinging compared to staggered application
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