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After opening, store bacteriostatic water vials upright at controlled room temperature, typically 15C30C (59F86F), away from direct light and moisture
or reta
Many patients with neurologic signs of vitamin B12 deficiency do not have readily detectable hematological abnormalities, such as megaloblastic anemia (also known as macrocytic anemia) or neutrophils with hypersegmented nuclei (151
ICH Q2(R2): Validation of Analytical Procedures
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