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The glycine component may partially offset this side effect, though clinical data specifically on compounded tirzepatide-glycine combinations for sleep improvement remains limited

Study 1: The SURMOUNT-1 Trial (Obesity) Title: TZ Once Weekly for the Treatment of Obesity Summary: This landmark Phase 3 trial demonstrated that Tirzepatide achieved substantial reductions in body weight (up to 20.9%) in non-diabetic subjects, significantly outperforming placebo