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Description

Alternative receptor tyrosine kinases activation The receptor tyrosine kinase family composes of many collaborative members such as EGFR, ErbB2/3/4, MET, Axl, PDGF receptor (PDGFR), and IGF-IR, which share some effectors including PI3K/Akt/mTOR, Ras/Raf/Mek/Erk, Src, and JAK/STAT