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The implementation of these factors depends on various environmental influences, such as stress, smoking, bacterial and viral infections, chemical pollutants, as well as dietary iodine (1, 3)

A GLP-1-only plan targets one pathway related to appetite and digestion, while GIP + GLP-1 targets two pathways that may enhance metabolic response and insulin sensitivity for some people

Treatment discontinuation due to gastrointestinal events occurred in a minority of patients, and overall, serious adverse events were similar to those with the placebo

This mechanism would bypass the gastrointestinal tract and provide steady-state drug levels over an extended period