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I have added a slide from a Novo Nordisk presentation illustrating that participants requiring dose reductions during maintenance tended to enter the study with BMI levels distributed slightly within a lower rangefurther supporting individualized maintenance dosing strategies

Poor sleep increases ghrelin (hunger hormone) levels and reduces the appetite-suppressing effects of GLP-1 receptor activation

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If your body does not make enough insulin, or if it does not use the insulin it makes effectively, this results in the condition called type 2 diabetes (diabetes mellitus)