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Long-term data is still emerging, but one study published in the May issue of the Journal of Managed Care and Specialty Pharmacy (JMCP) identified that approximately two-thirds of patients treated with GLP-1 RAs for obesity experienced at least a 60-day gap in treatment within the first year and just over one-quarter of patients remained at least 80% adherent to therapy

Patients with significant kidney or liver disease would typically require closer monitoring

Verallo-Rowell V

Key takeaways Contrave (naltrexone/bupropion) is a twice-daily oral tablet, while Wegovy (semaglutide) is either a weekly injection or a daily oral tablet