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C5a receptor (CD88) blockade protects against MPO-ANCA GN

Current etiological comprehension and therapeutic targets of acetaminophen-induced hepatotoxicity

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This inhibitory effect is attributed to the activation of the adenosine monophosphate (AMP)-activated protein kinase (AMPK) signaling pathway and the concurrent downregulation of forkhead Box A1 (FOXA1) and sonic hedgehog (SHH) expression (Xie et al., 2020)

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