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In this review, we have relied on the interpretations provided by the original authors of the referenced studies while synthesizing the results, however, we acknowledge the limitations of these paradigms and the need for caution in their interpretation

The Importance of a Gradual Reduction Gradual reduction of GLP-1 medication is an important aspect to think about when discontinuing its use in order to minimize potential withdrawal effects and guarantee a safe shift

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However, experts in the area generally concur that a combination of data from multiple endpoints is needed to discriminate sensitizing and/or irritant substances in vitro