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Hypoxia-inducible regulation of a prodrug-activating enzyme for tumor-specific gene therapy
Most of the GSH (8085%) is stored in the cytosol, 1015% in the mitochondria (with an equal concentration between matrix and cytosol, thus requiring specific transport systems) and a small part in the endoplasmic reticulum (ER) ( 2.1
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By supporting the growth and repair of enterocytes, glutamine supplementation helps prevent the translocation of pathogens and toxins from the gut into the bloodstream, thereby reducing the risk of infections [8, 41, 65]
