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Across all 32 articles included in this study, there was significant variability as to the subjects included, tests used, level of confounding factors, measurements and patient demographics obtained, etc
In diseases where amino-acid metabolizing enzymes are dysfunctional or absent (e.g., propionic acidemia and methylmalonic acidemias characterized by neurological symptoms, muscle weakness and low energy) C3 accumulates, and higher blood levels are used as a screening tool
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The gastroparesis-like effects of GLP-1 agents are very real and have directly contributed to new or worsening GERD in countless patients
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