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Mootha, V

If you are on Linzess for treatment of constipation, make sure you consult your healthcare provider before starting any new medication or making changes to your medication dosages

The goal is to keep the dose right for ongoing weight loss while staying safe and tolerable

A study exploring the physiological mechanisms underlying tirzepatide in the treatment of T2D showed that, compared to the GLP-1RA semaglutide, tirzepatide significantly improves both insulin secretion rates and insulin sensitivity, which indicates synergistic anti-hyperglycemic efficacy as an agonist of both the GLP-1 and GIP receptors [13]