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Given the binary nature of side effect phenotype definitions, we fitted multi-variable logistic regression models (equivalent to a generalized linear model with a binomial family and logit link function)
Blood Sugar Control: Stimulates insulin release and reduces glucagon production, contributing to improved blood sugar control in individuals with type 2 diabetes
Mitochondrial support: Enhances mitochondrial respiration and reduces reactive oxygen species, at least in aging fibroblast models
Finally, most studies are preclinical, based on cell and animal models, and lack valid clinical evidence
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