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In neurons, HGF/c-Met signaling supports synaptic plasticity, dendritic spine formation, and various aspects of learning and memory
In the previous phase I experiment, CB-839 combined with cabozantinib demonstrated good safety and efficacy in the treatment of metastatic renal cell carcinoma (RCC) (Tannir et al., 2018
Glutathione shifts the process of melanogenesis from eumelanin to pheomelanin through the reaction between thiol and dopaquinone groups causing formation of sulfhydryl-dopa conjugates[] [Figure 2]
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