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These medications are absorbed and metabolized through pathways that do not overlap with tirzepatide pharmacokinetics

These values were log 2 transformed, and the median of the biological replicates was reported as the final log 2 (fold change) value

Adults with type 2 diabetes, a body mass index (BMI) of 30 or above, or a BMI of 27 or above with health-related complications such as high blood pressure and sleep apnea might consider treatment with a GLP-1 medication