tirzepatide vs semaglutide weight loss study Semaglutide: 2025 NEJM Reveals Superior Tirzepatide causes more weight loss

Severe nausea on GLP-1 medications combined with illness-related vomiting creates a dangerous situation where: Dehydration can develop rapidly You cannot absorb oral medications or nutrients The GLP-1 medication may worsen gastrointestinal symptoms Risk of electrolyte imbalances increases When to seek emergency care : If you cannot keep any fluids down for 12+ hours, notice dark urine, feel dizzy upon standing, or have a rapid heartbeat, seek medical attention immediately

This drug may cause side effects, including nausea/vomiting, diarrhea, constipation, headache, and dyspepsia

For people trying to start or continue taking GLP-1 RA medication, access issues are incredibly distressing, especially because GLP-1 RAs are meant to be taken regularly and long-term

But the drug form of GLP-1, known as GLP-1 agonists, can last up to 14 hours in your body