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Melatonin is most useful for circadian rhythm disruption and difficulty falling asleep, less so for middle-of-night awakenings

2 The Role of the Intestine in Metabolic Homoeostasis Apart from its role in nutrient digestion and absorption, the gastrointestinal tract (GIT) functions as a physical barrier to prevent undesirable luminal components, such as pathogens, dietary antigens and microbiota from entering the body ( Figure 1 )

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