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Some researchers have experimented with twice-daily split dosing (1 mg morning, 1 mg evening) to maintain more consistent plasma levels, particularly in protocols targeting systemic endpoints like wound healing or hair follicle stimulation
Regarding Spitzoid melanoma diagnosis, a recent description of five new histopathologic subtypes of Spitzoid melanomagenuine, uniform, packed, polypoid, and pigmentedaims to provide useful parameters to improve diagnostic confidence [49]
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