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Neuroendocrinology (2022) 112(7):673701
In REDEFINE 1, the combination produced larger average weight loss than either compound alone 20.4% with CagriSema versus 14.9% with semaglutide alone and 11.5% with cagrilintide alone, all under the treatment-policy estimand
Studies have shown that this method, combined with controlled progressive Achilles tendon loading, can significantly reduce pain and improve overall function
Combined total remains safe for most individuals
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