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If side effects are significant, holding at 5 mg for another four weeks before attempting escalation is perfectly reasonable

A separate condition, nonarteritic anterior ischemic optic neuropathy (NAION), has also been linked to semaglutide in newer research

Zepbound received FDA approval specifically for adults with moderate-to-severe obstructive sleep apnea who also have obesity

Although the true value of the cardiovascular effects of treatment in these study populations is not known, the scenario analyses conducted suggest that oral semaglutide is associated with additional benefits compared with both empagliflozin and sitagliptin, although the magnitude of this effect is uncertain