Where you see weight-loss B12 protocols marketed (especially in the United States), they are almost always paired with calorie restriction and other interventions doing the actual work
Then glutathione injections are the way to go
A glutathione drip, on the other hand, involves adding glutathione directly into the IV bag so it is infused over the entire session
Further, BBB disrupts transiently by breaking down the TJs so that it can permit transport of various molecules, ultrasounds (trans-skull focused ultrasound (FUS), MRI, or hyperosmotic solutions (like mannitol, arabinose, lactamide, saline, urea, DMSO, ethanol, glycerol, polysorbate-80, and X ray-irradiation, etc.)