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Current data indicated that this question still cannot be conclusively answered as both autophagy and necroptosis are considered to have a Janus-faced role in tumorigenesis and cancer treatment

doi: 10.3389/fnut.2025.1693167 Received 26 August 2025 Accepted 03 November 2025 Published 28 November 2025 Volume 12 - 2025 Edited by Giacomo Di Matteo, Sapienza University of Rome, Italy Reviewed by Zhili Liang, Guangdong Food and Drug Vocational College, China Emmanuel Kingsley Darkwah, Missouri University of Science and Technology, United States Updates Copyright 2025 Semchyshyn

They establish a robust technical foundation for the clinical translation of targeted therapies based on engineered milk exosomes (Cui et al., 2023

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