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Newly identified monogenic entities such as DADA2 (deficiency of adenosine deaminase 2) and VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome also exhibit vasculitic features and are associated with a high risk of thrombosis
Fatigue is listed as a reported adverse reaction for some GLP-1 receptor agonists, particularly those used at higher doses for weight management such as semaglutide (Wegovy) and liraglutide (Saxenda)
Tirzepatide (Mounjaro, Zepbound) is technically a dual GIP/GLP-1 receptor agonist, hitting two incretin receptors instead of one, which explains its superior weight loss outcomes in clinical trials
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