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Supply and Shortages Like the rest of the world, Canada has faced periods of high demand that led to temporary shortages

However, the long-term treatment with GLP-1RAs may reduce the insulin levels in both T2DM (122) and prediabetic patients (123), owing to the glycemic normalization and increased insulin sensitivity in these patients

Future study should focus on personalized ketogenic strategies integrated with broader lifestyle and nutritional frameworks

Although only one GLP1RA has been approved by the FDA in the Philippines for weight loss alone (without diabetes), patients have been clamoring to acquire these medications to hasten weight reduction