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Eating foods rich in glutathione precursors such as cysteine (found in high-protein foods), and sulfur-containing vegetables like broccoli, kale, and garlic can help
Common reports include soreness at the injection site, nausea, headache, and tiredness
Modulation of intestinal transport and absorption of topotecan, a BCRP substrate, by various pharmaceutical excipients and their inhibitory mechanisms of BCRP transporter
Disruption of this axis, by either pharmacological inhibition or genetic ablation, leads to ferroptotic cell death
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