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Pennisi M, et al

Acknowledgements Not applicable Funding This study was supported by the Funding by Science and Technology Projects in Guangzhou (Grant Number: 202201020081)

Eat dinner at least two to three hours before bed to allow for the slowed gastric emptying that tirzepatide causes

Cycle Guidelines Approach Standard Duration 8-12 weeks Off Period 4-8 weeks Best For General research context Approach Extended Duration 12-16 weeks Off Period 4-8 weeks Best For Longer observation windows Time off is commonly used to limit receptor desensitization

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