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Employer plans that do cover it often layer on prior-authorization requirements, documented BMI thresholds, step-therapy rules requiring a failed attempt with an older medication, and annual or lifetime caps
68 Overactivation of complement pathways promotes inflammation, immune cell recruitment, and kidney injury 69 while triggering downstream pathways involving ROS, NF-B, and protein kinase C (PKC)
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doi: 10.1152/ajpheart.00278.2021, 112
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