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The VA's trial adds to a growing body of ongoing research into GLP-1 medications' effects well beyond their original diabetes and weight-loss indications, as the drugs have continued attracting significant scientific and public interest since their initial approval and rapid rise in popularity in recent years
Novos GLP-1 revenue generated around $35 billion in 2025, about 75% of the companys annual revenue
Retatrutide produces substantially more weight loss
This downregulates the neuroinflammatory cascade and suppresses oxidative stress and actively promotes neuroplasticity and cellular survival within, in particular, the hippocampus
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