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Whole foods provide additional health benefits beyond just the target nutrient
Most adults are chronically low in B12 because common medications (aspirin, antacids, PPls, antibiotics, metformin) interfere with their absorption in the stomach
IGF-1 exerts its biological effect through binding to the IGF1 receptor (IGF1R), its effect is modulated through interaction with a group of binding proteins (IGFBPs), which tend to inhibit the effect of IGF-1 [2]
It is important to consider potential variations in efficacy among subjects and potential differences in potency compared to injectable formulations
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