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IGF-1, as a nutrient-responsive growth factor, activates NF-B and the expression of downstream genes (Ccdn1, Vegf, Birc5 and Ptgs2) to promote the growth of pancreatic cancer in vitro and in vivo (88)
2023 Jun 23-26
They would be teammates on paper because CLA may increase fatty acid availability and L-carnitine helps deliver fatty acids to mitochondria, but human clinical trials showing consistent additive benefit are limited so the team idea is plausible but not proven
For this stack specifically, we can track IGF-1 through our optimization panel and use InBody scans to confirm the body-composition changes are real, not just a feeling
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