S2 additional material).7,8 The incidence of PsO and HS has increased in western countries in recent decades.9,10 Obesity has increased in parallel, and could be responsible, at least partially, for the aforementioned increase.8 Psoriasis and obesity The prevalence of obesity is higher among patients with PsO than in the general population.1118 In addition, obesity increases the risk of PsO,6,19,20 the incidence of which could be twice as great in patients with grade II/III obesity compared with subjects with normal weight.21 Among the molecular mediators at the intersection between the 2 conditions are 3 adipokinesleptin, resistin, and adiponectinwhose levels impact the severity of PsO in patients with obesity.2224 Many complications associated with obesity are also associated with PsO
Compounded semaglutide vs brand-name: the real differences The price gap between compounded semaglutide and brand-name versions is massive
Journal of the American Society of Hypertension
By integrating the latest research, we aim to provide a conceptual framework for future studies and therapeutic strategies targeting Trx-mediated regulation of cell death