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While Mounjaros clinical results are promising, differentiation versus Ozempic is not clean cut, as clinical results appear to be dose dependent, and Ozempic may have a slight advantage in terms of gastrointestinal (GI) tolerability and dropout rates (discontinuation rates due to adverse events in tirzepatide arms were 5.1% 7.9% compared to 3.8% in semaglutide cohort)

In this context, the CS regulation at both the enzyme and the gene level plays a pivotal role in the metabolic flux modulation of tumors, and scientists can target them for therapeutic purposes