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What You Need to Know Youre seeing amazing results with GLP-1 medications, and the numbers on the scale are finally moving
2013 May 1;1830(5):3317-28
You will still need to strive for a caloric deficit or balance to maintain your desired weight
(Left) In liver cells, GLP-1 can mediate cholesterol efflux by acting directly on LXR, or by inducing an increase in ATP-binding cassette transporter A1 (ABCA1) mRNA through Ca2+/calmodulin (CaM)-dependent protein kinase kinase/CAM-dependent protein kinase IV/Prolactin regulatory element binding (CaMKK/CaMKIV/PREB), increasing apolipoprotein AI (apo AI) mRNA and promoter expression, and increasing apo AI secretion, thereby mediating intracellular cholesterol efflux
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