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When hair loss is linked to a hormonal cause like PCOS (polycystic ovary syndrome), doctors often reach for spironolactone instead, an androgen-receptor blocker rather than a 5-alpha-reductase inhibitor
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In addition, expression of monocarboxylate transporter 1 (MCT1), a key butyrate transporter, is downregulated in colonic epithelial cells from patients with Crohns disease, further compromising butyrate uptake (Ferrer-Picon et al., 2020)
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