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BRIEF SUMMARY OF THE INVENTION The invention includes a method of treating sexual dysfunction in a patient, including the steps of oral administration of a type V phosphodiesterase (PDE-5) inhibitor and non-oral administration of a melanocortin receptor agonist, preferably a melanocortin 3 and/or melanocortin 4 receptor agonist

J Am Soc Nephrol 28(4):10231039 Layton AT, Vallon V (2018) Renal tubular solute transport and oxygen consumption

Transport of ALCAR across cell membranes, including the blood-brain barrier, is primarily mediated by the organic cation/carnitine transporter 2 (OCTN2, encoded by SLC22A5), a sodium-dependent transporter expressed on the luminal side of endothelial cells [5]