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74 TianF.ZhangY.WangL
Decreased exercise tolerance during treatment was linked with greater lean body mass loss in both groups, but more so with tirzepatide, and higher doses, longer treatment and pre-existing musculoskeletal pain were also associated with larger lean mass declines for both drugs
It preserves and potentially builds muscle mass despite caloric restriction, increases insulin sensitivity independent of weight loss, improves bone density, and maintains or increases resting metabolic rate
However, women supplementing l carnitine later that age were seen to have improved bone health
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