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The peptides specific targeting of NNMT-expressing adipocytes allows for a localized metabolic shift without widespread systemic overstimulation, presenting a unique model for selective fat mass modulation studies
Published trials reported headache, fatigue, dizziness, mild stomach symptoms, and mild injection-site reactions
There is also a longevity fervor now, with longevity clinics, longevity companies (recently reviewed here), and longevity doctors
No serious adverse events, liver enzyme elevations, or cardiovascular changes were documented in the Phase 1 safety study published in the Journal of Clinical Endocrinology & Metabolism in 2024
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