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A comparative study of obese and lean rats found that lean rats showed greater drops in estrogen and vitamin D and higher urinary calcium excretion after weight loss, suggesting increased sensitivity to calcium disturbances

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Understanding the Risks of Misuse and Off-Label Prescribing The growing trend of individuals who are not medically eligible seeking and sometimes obtaining GLP-1 medications like Ozempic for purely cosmetic weight loss highlights a serious concern regarding misuse and inappropriate off-label prescribing

Bowers and colleagues demonstrated in normal men that a GH-releasing peptide given with GHRH produced GH responses substantially greater than the sum of either agent alone, and inferred from that supra-additivity that the two act through independent mechanisms