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Therefore, TIR is considered an ineffective strategy for addressing DXN-induced cognitive deficits and oxidative stress

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They also looked at biochemical markers, including C-reactive protein (CRP), glucose and haemoglobin A1c (HbA1c) levels

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This is comparable to the ~17.5% observed at 24 weeks in the Phase 2 obesity trial, reflecting the well-documented attenuation of weight loss in people with type 2 diabetes

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