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however, there was severe cell death when both cystine and GSH were depleted (Fig
Figure 3 3.5 Control analyses for age or TSH level as confounding factors In addition to the above planned statistical tests, we conducted two post hoc partial correlation analyses to examine possible confounding effects of age or TSH level as confounding factors
POPs are mainly excreted through conjugation with GSH and this mechanism is extremely important for the health status, since exposure to POPs has been associated to diabetes, cardiovascular diseases and many other chronic diseases ( ROS production can occur at several intracellular sites but, for most cells, takes place in the mitochondria and the mitochondrial electron transport chain is the main cellular process of ROS generation in physiological circumstances ( 2 O 2 )
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