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A small amount of the drug is metabolized via the cytochrome P-450 pathway (to be specific, CYP3A4 and CYP2E1) into NAPQI, which is extremely toxic to liver tissue, as well as being a strong biochemical oxidizer
Cobalamin deficiency results in the decrease of this conversion, resulting in high plasma levels of homocysteine, which is associated with a higher risk of cerebrovascular disease, depression, dementia, cellular stress, and apoptosis (25, 27, 64, 70)
With age as a covariate, the Spearman rho values remained practically unchanged (differed by less than 0.02) regardless of if we excluded or included the covariate, separately for all 4 conditions [Hypothyroidism/CFS x Before/After L-carnitine]
Jenny Arteta Napakanta ako sa sobrang ganda ng effect sakin ng KB
