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If needed, add a little more medication to get the correct prescribed dose

It works by calming down an enzyme (NNMT) that slows the metabolism in people with obesity, diabetes, or aging

Short-term weight increases during retatrutide treatment are most commonly caused by fluid retention, constipation, normal daily weight fluctuation, or inadequate appetite suppression during early dose titration not necessarily treatment failure

The choice between these medications would depend on individual health goals, tolerance to side effects, and availability, with retatrutides future market entry contingent on successful trial outcomes and regulatory approval.