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Reduced means the glutathione is in its active, scavenging form
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A Phase 2 trial (NCT01311518) was designed to test RGN-352 in ~75 heart attack patients, but was placed on FDA clinical hold in 2011 due to manufacturing (GMP) compliance issues at the contract site not safety concerns with the drug itself
Four weeks after UUO surgery, the mice were euthanized at 14 d
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