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Br J Pharmacol (2014) 171(10):255267.10.1111/bph.12512 26 MalhotraR
Pros: Extended half-life compared to unmodified MGF, in theory allowing fewer, more practical dosing intervals Mechanism aligns with well-studied endogenous muscle-repair biology (satellite cell activation, IGF-1 pathway) Widely available from research-chemical vendors for lab/research purposes Cons: No FDA approval, no completed human clinical trials, and no regulator-reviewed safety or efficacy data Prohibited in competitive sport under WADA growth-factor rules Product quality and purity vary significantly between unregulated research-chemical suppliers Side Effects: Not well characterized due to the absence of an approved label
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